When unconscious, the brain is anything but ‘silent’
The cerebral cortex is thought to be the seat of conscious processing in the brain. Rather than being inactivated, specific cells in the cortex show higher spontaneous activity during general anesthesia than when awake, and this activity is synchronized across those cortical cells. Improving our understanding of the neuronal mechanisms of general anesthesia could lead to better anesthetic drugs and improved surgical outcomes.
Feedback disruptors—a new class of therapeutics—throw drug resistance for a loop
Viruses in the herpesvirus family are leading causes of birth defects, blindness, and failed organ transplants worldwide. Antiviral drugs can combat these viruses, but patients often develop resistance to the drugs—rendering them ineffective.
Skin drug treatments may regress dangerous birthmarks and prevent melanoma
About one in 20,000 infants is born with what's called a congenital giant nevus—a huge, pigmented mole that may cover much of the face and body. Due to the mole's appearance and its risk of later developing into skin cancer, many patients decide to have their children undergo extensive surgery to remove the entire lesion, which can cause large and permanent scars. Researchers led by investigators at Massachusetts General Hospital (MGH) recently created multiple preclinical models of this condition and used them to show that several drugs can be applied to the skin to cause the lesions to regress, and one topical drug also protected against skin cancer. Their findings are published in the journal Cell.
When unconscious, the brain is anything but ‘silent’
The cerebral cortex is thought to be the seat of conscious processing in the brain. Rather than being inactivated, specific cells in the cortex show higher spontaneous activity during general anesthesia than when awake, and this activity is synchronized across those cortical cells. Improving our understanding of the neuronal mechanisms of general anesthesia could lead to better anesthetic drugs and improved surgical outcomes.
Feedback disruptors—a new class of therapeutics—throw drug resistance for a loop
Viruses in the herpesvirus family are leading causes of birth defects, blindness, and failed organ transplants worldwide. Antiviral drugs can combat these viruses, but patients often develop resistance to the drugs—rendering them ineffective.
Skin drug treatments may regress dangerous birthmarks and prevent melanoma
About one in 20,000 infants is born with what's called a congenital giant nevus—a huge, pigmented mole that may cover much of the face and body. Due to the mole's appearance and its risk of later developing into skin cancer, many patients decide to have their children undergo extensive surgery to remove the entire lesion, which can cause large and permanent scars. Researchers led by investigators at Massachusetts General Hospital (MGH) recently created multiple preclinical models of this condition and used them to show that several drugs can be applied to the skin to cause the lesions to regress, and one topical drug also protected against skin cancer. Their findings are published in the journal Cell.
Discovery reveals blocking inflammation may lead to chronic pain
Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain.
Perinatal Mental Health Support for Parents of Color: Interview with Lauren Elliott, Founder of Candlelit Therapy
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Wearable Sweat Sensor Warns of Impending Cytokine Storm
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Cryoablation for Treatment of Heavy Menstrual Bleeding: Interview with Ric Cote, CEO of Channel Medsystems
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Advanced Multi-Organ Chip for Personalized Medicine
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Leg Sleeve for Neurological Mobility Issues: Interview with Jeremiah Robison, Cionic CEO
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Molecular Robots Swarm to Deliver Cargo
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Wireless Implant for Anti-Cancer Photodynamic Therapy
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Smartphone App to Diagnose Neurological Disorders
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Helping Digital Health Companies Win Regulatory Approvals: Interview with Ruby Gadelrab, CEO of MDisrupt
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Soft Robotic Sleeve for Lymphedema Treatment
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Heart Chamber on a Chip
Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.
Discovery reveals blocking inflammation may lead to chronic pain
Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain.
The 14 Best Flatware Sets for Dining at Home
These are the best silverware options to show off your aesthetic, from modern pieces to heirloom-worthy picks. Each product we feature has been independently selected and reviewed by our editorial team. If you make a purchase using the links included
Apple CarPlay will let you pay for gas from your driver’s seat
During its WWDC event a few weeks ago, Apple announced iOS 16, highlighting a “next-generation” CarPlay experience that automakers might not be ready for any time soon. It also announced a new “fueling and driving tasks apps” feature that you will ac
Why You're Cutting Chicken Wrong, According To Science
There comes a time in every home cook's life when they're faced with the following quandary: to adapt a recipe based on the latest tips and tricks relayed on the internet, or to ignore them and go with what feels right? That is the question
Crypto Nonsense: Why Keanu? Why?
The action movie star and his partner Alexandra Grant are trying to make the metaverse—and NFTs—a little more inclusive. Just more Crypto Nonsense.
The post Crypto Nonsense: Why Keanu? Why? first appeared on Science Radars.
Crypto Nonsense: Why Keanu? Why?
The action movie star and his partner Alexandra Grant are trying to make the metaverse—and NFTs—a little more inclusive. Just more Crypto Nonsense.
See what our national parks first looked like
From sweeping views of the Grand Canyon to stunning waterfalls in Yosemite, these vintage photos capture timeless beauty of national parks in the United States.
A day in the Okavango Delta
What’s it like to arrive in one of the most pristine, unspoiled oases in all of Africa? Batswana photojournalist Thalefang Charles takes you there.
General Grant’s surprising rise from cadet to commander
Early in the Civil War, Union forces were struggling in the East but winning in the West, where a relentless Ulysses S. Grant scored victory after victory to ascend through the ranks.
